HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-bromo-2-methylpropionate → methyl 2-methyl-2-(4-nitro-1H-imidazol-1-yl)propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-bromo-2-methylpropionate | HCID 90097 | — |
| Reactant | HCID 178526856 | HCID 178526856 | — |
| Product | methyl 2-methyl-2-(4-nitro-1H-imidazol-1-yl)propanoate | HCID 67164903 | — |
Reaction Steps
4-nitroimidazole was alkylated with 2-Bromo-2-methyl-propionic acid methyl ester to provide the title compound: 1H NMR (400 MHz, CDCl3) 1.89 (s, 6H), 3.78 (s, 3H), 7.59 (d, 1H, J=1.7 Hz), 7.89 (s, 1H, J=1.7 Hz); MS 214.1 m/z (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07795447B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-01fd58d3c0374be796cb3f0c53fea66c |
| Source note | uspto-grants-2010_09 |