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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1714279Generated: November 3, 2026

Methyl bromoacetate → Methyl (4-nitro-1-imidazolyl)acetate

https://huagongshe.com/reaction/1714279

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl bromoacetateHCID 60984—
ReactantHCID 178526856HCID 178526856—
ProductMethyl (4-nitro-1-imidazolyl)acetateHCID 3103698—

Reaction Steps

4-nitroimidazole was alkylated with bromo-acetic acid methyl ester to provide the title compound: 1H NMR (400 MHz) 3.82 (s, 1H), 4.80, (s, 2H), 7.47 (d, 1H, J=1.7 Hz), 7.84 (d, 1H, J=1.7 Hz); gc/ms m/z 185 (M).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07795447B2
Source datasetuspto-grants-2010_09
ORD IDord-f63c817c82e4476abfab435e6bead2d6
Source noteuspto-grants-2010_09