Morpholine → 4-[2-Methyl-2-(4-nitro-imidazol-1-yl)-propyl]-morpholine

HRID 1714283Notes

Reaction equation

[CH3:1][C:2]([N:6]1[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[N:8]=[CH:7]1)([CH3:5])[CH:3]=O.[NH:14]1[CH2:19][CH2:18][O:17][CH2:16][CH2:15]1>>[CH3:1][C:2]([N:6]1[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[N:8]=[CH:7]1)([CH3:5])[CH2:3][N:14]1[CH2:19][CH2:18][O:17][CH2:16][CH2:15]1

Participants

Reactant 2

HCID 8083Morpholine

HCID 866008092-Methyl-2-(4-nitro-imidazol-1-yl)-propionaldehyde

Product 1

HCID 671640894-[2-Methyl-2-(4-nitro-imidazol-1-yl)-propyl]-morpholine

Procedure

2-Methyl-2-(4-nitro-imidazol-1-yl)-propionaldehyde was reacted with morpholine to provide the title compound: MS m/z 255.1 (M+1)

Sources & evidence

ORD record: ord-3b315370622e4628a2bf3a4fa8d07aa4
Source dataset: uspto-grants-2010_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07795447B2

Reaction notes

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