Acetic Acid → 6-(2,6-dichlorophenyl)-2-[(2,3-dihydro-6-benzofuranyl)amino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one

HRID 171435Notes

Reaction equation

HRID 171435 reaction equation
[CH3:35][C:36](=[O:37])[OH:38].[Cl:1][c:2]1[c:3](-[c:9]2[cH:10][c:11]3[c:12]([n:13][c:14]([S:17]([CH3:18])(=[O:19])=[O:20])[n:15][cH:16]3)[n:21]([CH3:24])[c:22]2=[O:23])[c:4]([Cl:8])[cH:5][cH:6][cH:7]1.[O:25]1[CH2:26][CH2:27][c:28]2[c:29]1[cH:30][c:31]([NH2:34])[cH:32][cH:33]2>>[Cl:1][c:2]1[c:3](-[c:9]2[cH:10][c:11]3[c:12]([n:13][c:14]([NH:34][c:31]4[cH:30][c:29]5[c:28]([cH:33][cH:32]4)[CH2:27][CH2:26][O:25]5)[n:15][cH:16]3)[n:21]([CH3:24])[c:22]2=[O:23])[c:4]([Cl:8])[cH:5][cH:6][cH:7]1

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 105961576-(2,6-Dichlorophenyl)-8-methyl-2-methylsulfonyl-8H-pyrido[2,3-d]pyrimidin-7-oneHCID 123690442,3-Dihydro-1-benzofuran-6-amine

Product 1

HCID 177473236-(2,6-dichlorophenyl)-2-[(2,3-dihydro-6-benzofuranyl)amino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one

Sources & evidence

ORD record
ord-dc9881d1e1c944e983020466460c4ce3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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