4-(2,3-Dichlorophenoxy)piperidine → HCID 178523665, compound

HRID 1714407Notes

Reaction equation

HRID 1714407 reaction equation
O=[CH:2][CH2:3][C@H:4]1[CH2:9][CH2:8][C@H:7]([NH:10][C:11]([C:13]2[C:22]3[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=3)[N:16]=[CH:15][CH:14]=2)=[O:12])[CH2:6][CH2:5]1.[Cl:23][C:24]1[C:36]([Cl:37])=[CH:35][CH:34]=[CH:33][C:25]=1[O:26][CH:27]1[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]1>>[Cl:23][C:24]1[C:36]([Cl:37])=[CH:35][CH:34]=[CH:33][C:25]=1[O:26][CH:27]1[CH2:28][CH2:29][N:30]([CH2:2][CH2:3][C@H:4]2[CH2:9][CH2:8][C@H:7]([NH:10][C:11]([C:13]3[C:22]4[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=4)[N:16]=[CH:15][CH:14]=3)=[O:12])[CH2:6][CH2:5]2)[CH2:31][CH2:32]1

Participants

3

Reactant 2

HCID 113340744-(2,3-Dichlorophenoxy)piperidineHCID 178520748HCID 178520748, compound

Product 1

HCID 178523665HCID 178523665, compound

Procedure

The title compound was prepared analogously to example 71 using quinoline-4-carboxylic acid trans-[4-(2-oxo-ethyl)-cyclohexyl]-amide and 4-(2,3-dichloro-phenoxy)-piperidine as starting materials.

Sources & evidence

ORD record
ord-fb5ac9750c764e7a9f10c54db2ca453f
Source dataset
uspto-grants-2010_09
Patent number
US07795437B2

Reaction notes

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