4-(3,4-Dichlorophenoxy)piperidine → HCID 178523666, compound

HRID 1714408Notes

Reaction equation

HRID 1714408 reaction equation
O=[CH:2][CH2:3][C@H:4]1[CH2:9][CH2:8][C@H:7]([NH:10][C:11]([C:13]2[C:22]3[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=3)[N:16]=[CH:15][CH:14]=2)=[O:12])[CH2:6][CH2:5]1.[Cl:23][C:24]1[CH:25]=[C:26]([CH:34]=[CH:35][C:36]=1[Cl:37])[O:27][CH:28]1[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]1>>[Cl:23][C:24]1[CH:25]=[C:26]([CH:34]=[CH:35][C:36]=1[Cl:37])[O:27][CH:28]1[CH2:33][CH2:32][N:31]([CH2:2][CH2:3][C@H:4]2[CH2:9][CH2:8][C@H:7]([NH:10][C:11]([C:13]3[C:22]4[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=4)[N:16]=[CH:15][CH:14]=3)=[O:12])[CH2:6][CH2:5]2)[CH2:30][CH2:29]1

Participants

3

Reactant 2

HCID 37320424-(3,4-Dichlorophenoxy)piperidineHCID 178520748HCID 178520748, compound

Product 1

HCID 178523666HCID 178523666, compound

Procedure

The title compound was prepared analogously to example 71 using quinoline-4-carboxylic acid trans-[4-(2-oxo-ethyl)-cyclohexyl]-amide and 4-(3,4-dichloro-phenoxy)-piperidine as starting materials.

Sources & evidence

ORD record
ord-03921ecdfb0048049fafc2459e281b7e
Source dataset
uspto-grants-2010_09
Patent number
US07795437B2

Reaction notes

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