Formaldehyde → HCID 20027576, compound

HRID 1714695Notes

Reaction equation

HRID 1714695 reaction equation
[NH:1]1[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[CH2:7]=O.[CH3:9][O:10][C:11]1[CH:16]=[C:15]([CH:17]=[O:18])[CH:14]=[CH:13][C:12]=1[OH:19]>C(O)C>[OH:19][C:12]1[C:13]([CH2:7][N:1]2[CH2:6][CH2:5][O:4][CH2:3][CH2:2]2)=[CH:14][C:15]([CH:17]=[O:18])=[CH:16][C:11]=1[O:10][CH3:9]

Participants

5

Reactant 3

HCID 712FormaldehydeHCID 1183VanillinHCID 8083Morpholine

Product 1

HCID 20027576HCID 20027576, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

26.1 g (0.30 mol) of morpholine were added to 24.0 g (0.30 mol) of a 37% aqueous formaldehyde solution in 180 ml of ethanol. Then 30.4 g (0.20 mol) of 4-hydroxy-3-methoxybenzaldehyde (vanillin) were added. The reaction mixture was refluxed for one hour. After cooling the majority of the solvent was removed in a rotary evaporator. 250 ml of distilled water were added to the residue. After a certain time, a solid began to precipitate out, which was filtered out and dried.

Workup

  1. temperatureThe reaction mixture was refluxed for one hour
  2. temperatureAfter cooling the majority of the solvent
  3. customwas removed in a rotary evaporator
  4. addition250 ml of distilled water were added to the residue
  5. customto precipitate out
  6. filtrationwhich was filtered out
  7. customdried

Sources & evidence

ORD record
ord-4e4abc5994ee4628ba10c7ea5a1be616
Source dataset
uspto-grants-2010_09
Patent number
US07799096B2

Reaction notes

Loading…