Dimethylamine → HCID 59235872, compound

HRID 1714697Notes

Reaction equation

HRID 1714697 reaction equation
[CH3:1][NH:2][CH3:3].[CH2:4]=O.[Br:6][C:7]1[CH:8]=[C:9]([CH:12]=[CH:13][C:14]=1[OH:15])[CH:10]=[O:11]>C(O)C>[Br:6][C:7]1[CH:8]=[C:9]([CH:12]=[C:13]([CH2:1][N:2]([CH3:4])[CH3:3])[C:14]=1[OH:15])[CH:10]=[O:11]

Participants

5

Reactant 3

HCID 674DimethylamineHCID 712FormaldehydeHCID 763083-Bromo-4-hydroxybenzaldehyde

Product 1

HCID 59235872HCID 59235872, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

22.8 g (0.19 mol) of a 40% aqueous dimethylamine solution were added to 15.2 g (0.19 mol) of a 37% aqueous formaldehyde solution in 110 ml of ethanol. Then 25.0 g (0.12 mol) of 3-bromo-4-hydroxybenzaldehyde were added thereto. The reaction mixture was refluxed for 30 minutes and then stirred for 24 hours at room temperature. The batch was stored overnight at 0 to 5° C. in the refrigerator. The precipitated white solid was filtered out and dried.

Workup

  1. temperatureThe reaction mixture was refluxed for 30 minutes
  2. waitThe batch was stored overnight at 0 to 5° C. in the refrigerator
  3. filtrationThe precipitated white solid was filtered out
  4. customdried

Sources & evidence

ORD record
ord-c2ab2773537645a79f7754541c8a31be
Source dataset
uspto-grants-2010_09
Patent number
US07799096B2

Reaction notes

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