Formaldehyde → 2,3,4-Trihydroxy-5-(pyrrolidin-1-ylmethyl)benzaldehyde

Participants

Reaction Steps

17.1 g (0.24 mol) of pyrrolidine were added to 19.2 g (0.24 mol) of a 37% aqueous formaldehyde solution in 140 ml of ethanol. Then 25.0 g (0.16 mol) of 2,3,4-trihydroxybenzaldehyde were added thereto. The reaction mixture was refluxed for one hour, developing a dark brown color. After cooling, a beige-brown solid precipitated out, which was filtered out and dried.

Provenance & Evidence