反应详情

Into 7N-ammonia-methanol solution, 170 g of ethyl 2-oxocyclohexanecarboxylate was added and stirred for an overnight at room temperature. Distilling the solvent off under reduced pressure, the resulting crude crystalline product was recrystallized from ethyl acetate-n-hexane to provide 152 g (90%) of ethyl 2-aminocyclohex-1-enecarboxylate.

1. distillationDistilling the solvent off under reduced pressure
2. customthe resulting crude crystalline product was recrystallized from ethyl acetate-n-hexane