Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | HCID 23155766 | HCID 23155766 | — |
| Product | HCID 23155747 | HCID 23155747 | 201.4% |
Reaction Steps
A mixture of 4.32 g of 2-[4-(4-quinolin-2-ylpiperazin-1-yl)-pentanoylamino]benzoic acid as synthesized in above Step 7-15-A and 3.06 g of acetic anhydride was stirred at 80° C. for an hour, and the solvent was distilled off under reduced pressure to provide 4.17 g (100%) of 2-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]-3,1-benzoxazin-4-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07799775B2 |
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| Source dataset | uspto-grants-2010_09 |
|---|
| ORD ID | ord-476980bd26f141b8b21c52601236f012 |
|---|
| Source note | uspto-grants-2010_09 |
|---|
