4-(4-Fluoro-benzyl)-piperidine → HCID 23630220, compound
Reaction equation
Cl[C:2]1[N:7]=[N:6][C:5]([C:8]([NH:10][CH2:11][CH2:12][CH:13]([CH3:15])[CH3:14])=[O:9])=[CH:4][CH:3]=1.[F:16][C:17]1[CH:29]=[CH:28][C:20]([CH2:21][CH:22]2[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]2)=[CH:19][CH:18]=1>>[F:16][C:17]1[CH:18]=[CH:19][C:20]([CH2:21][CH:22]2[CH2:23][CH2:24][N:25]([C:2]3[N:7]=[N:6][C:5]([C:8]([NH:10][CH2:11][CH2:12][CH:13]([CH3:15])[CH3:14])=[O:9])=[CH:4][CH:3]=3)[CH2:26][CH2:27]2)=[CH:28][CH:29]=1Participants
3
Procedure
The title compound was prepared in the same manner as described for Example 16 from 6-chloro-N-(3-methylbutyl)pyridazine-3-carboxamide and 4-(4-fluorobenzyl)piperidine. MS (+ESI) m/z 385 (MH+).
Sources & evidence
- ORD record
- ord-67b1c77ac64344de8660b3eef8abc190
- Source dataset
- uspto-grants-2010_09
- Patent number
- US07799787B2
Reaction notes
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