4-(2-Methoxy-benzyl)-piperidine → 6-[4-(2-Methoxybenzyl)piperidin-1-yl]-N-(3-methylbutyl)pyridazine-3-carboxamide

HRID 1714879Notes

Reaction equation

HRID 1714879 reaction equation
Cl[C:2]1[N:7]=[N:6][C:5]([C:8]([NH:10][CH2:11][CH2:12][CH:13]([CH3:15])[CH3:14])=[O:9])=[CH:4][CH:3]=1.[CH3:16][O:17][C:18]1[CH:30]=[CH:29][CH:28]=[CH:27][C:19]=1[CH2:20][CH:21]1[CH2:26][CH2:25][NH:24][CH2:23][CH2:22]1>>[CH3:16][O:17][C:18]1[CH:30]=[CH:29][CH:28]=[CH:27][C:19]=1[CH2:20][CH:21]1[CH2:26][CH2:25][N:24]([C:2]2[N:7]=[N:6][C:5]([C:8]([NH:10][CH2:11][CH2:12][CH:13]([CH3:15])[CH3:14])=[O:9])=[CH:4][CH:3]=2)[CH2:23][CH2:22]1

Participants

3

Reactant 2

HCID 111608404-(2-Methoxy-benzyl)-piperidineHCID 167337866-chloro-N-(3-methylbutyl)pyridazine-3-carboxamide

Product 1

HCID 576471256-[4-(2-Methoxybenzyl)piperidin-1-yl]-N-(3-methylbutyl)pyridazine-3-carboxamide

Procedure

The title compound was prepared in the same manner as described for Example 16 from 6-chloro-N-(3-methylbutyl)pyridazine-3-carboxamide and 4-(2-methoxybenzyl)piperidine. MS (+ESI) m/z 397 (MH+).

Sources & evidence

ORD record
ord-9920c0720d3541f19ef0de60accf6b9d
Source dataset
uspto-grants-2010_09
Patent number
US07799787B2

Reaction notes

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