Phenyl(piperidin-4-yl)methanone → 6-(4-benzoylpiperidin-1-yl)-N-(3-methylbutyl)pyridazine-3-carboxamide

HRID 1714880Notes

Reaction equation

HRID 1714880 reaction equation
Cl[C:2]1[N:7]=[N:6][C:5]([C:8]([NH:10][CH2:11][CH2:12][CH:13]([CH3:15])[CH3:14])=[O:9])=[CH:4][CH:3]=1.[C:16]1([C:22]([CH:24]2[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]2)=[O:23])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[C:22]([CH:24]1[CH2:29][CH2:28][N:27]([C:2]2[N:7]=[N:6][C:5]([C:8]([NH:10][CH2:11][CH2:12][CH:13]([CH3:15])[CH3:14])=[O:9])=[CH:4][CH:3]=2)[CH2:26][CH2:25]1)(=[O:23])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 226102Phenyl(piperidin-4-yl)methanoneHCID 167337866-chloro-N-(3-methylbutyl)pyridazine-3-carboxamide

Product 1

HCID 576471186-(4-benzoylpiperidin-1-yl)-N-(3-methylbutyl)pyridazine-3-carboxamide

Procedure

The title compound was prepared in the same manner as described for Example 16 from 6-chloro-N-(3-methylbutyl)pyridazine-3-carboxamide and phenyl(piperidin-4-yl)methanone. MS (+ESI) m/z 381 (MH+).

Sources & evidence

ORD record
ord-fe46db1f0e5a46889d287ee390e10440
Source dataset
uspto-grants-2010_09
Patent number
US07799787B2

Reaction notes

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