HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[D]azepin-7-OL → 5-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-2-pyridinecarbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[D]azepin-7-OL | HCID 10082081 | — |
| Reactant | 5-Iodopyridine-2-carbonitrile | HCID 37818397 | — |
| Product | 5-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-2-pyridinecarbonitrile | HCID 10018859 | — |
Reaction Steps
The title compound (E206) was prepared from 3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-ol (E3) and 5-iodo-2-pyridinecarbonitrile (Biochemical Journal, 1973, 131(4), 625) according to the method outlined for E177a; MS (ES+) m/e 320 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07799773B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-0143e73352604bc2abfe49ab527b2d93 |
| Source note | uspto-grants-2010_09 |