Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1714970Generated: October 25, 2026

1-(6-Chloropyridin-3-yl)ethan-1-one → 1-{6-[(3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-3-pyridinyl}ethanone

https://huagongshe.com/reaction/1714970

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(6-Chloropyridin-3-yl)ethan-1-oneHCID 2779698—
Reactant3-Cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[D]azepin-7-OLHCID 10082081—
Reactant6-(3-Cyclobutyl-2,3,4,5-tetrahydro-1h-benzo[d]azepin-7-yloxy)-nicotinonitrileHCID 10448642—
Product1-{6-[(3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-3-pyridinyl}ethanoneHCID 10065600—

Reaction Steps

Example 214 (E214) was prepared from 3-cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol (E3) and 1-(6-chloropyridin-3-yl)ethanone using the method described for Example 100 (E100); MS (ES+) m/e 337 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07799773B2
Source datasetuspto-grants-2010_09
ORD IDord-93bb0f9e760a404a866d51207c3c93cc
Source noteuspto-grants-2010_09