HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-hydroxy-4-methoxybenzoate → 1,1-Dimethylethyl 7-({2-(methyloxy)-5-[(methyloxy)carbonyl]phenyl}oxy)-1,2,4,5-tetrahydro-3H-3-benzazepine-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-hydroxy-4-methoxybenzoate | HCID 4056967 | — |
| Reactant | (3-(tert-Butoxycarbonyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)boronic acid | HCID 57440296 | — |
| Product | 1,1-Dimethylethyl 7-({2-(methyloxy)-5-[(methyloxy)carbonyl]phenyl}oxy)-1,2,4,5-tetrahydro-3H-3-benzazepine-3-carboxylate | HCID 57440301 | — |
Reaction Steps
The title compound was prepared from (3-{[(1,1-dimethylethyl)oxy]carbonyl}-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)boronic acid (E264, Step 2) and methyl-3-hydroxy-4-methoxybenzoate using the method of Example 264 Step 3; MS (ES+) m/e 328 [(M+H)—CO2tBu]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07799773B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-5334a76b0a2a4316bd2af364a2f89ea2 |
| Source note | uspto-grants-2010_09 |