Borane → HCID 24801135, compound

Participants

Reaction Steps

Borane (8 mL of 1M THF solution) was added to a solution of 3-[6-(3-fluoro-benzenesulfonyl)-naphthalen-1-yl]-propionamide in 20 mL THF. The reaction mixture was refluxed for five hours, then cooled and quenched by addition of 10% aqueous HCl (25 mL). The mixture was heated to reflux for one hour, then cooled and THF was removed under reduced pressure. The resulting precipitate was collected by filtration to give 0.42 g of 3-[6-(3-Fluoro-benzenesulfonyl)-naphthalen-1-yl]-propylamine. MS (M+H)=344.

Provenance & Evidence