HuagongsheHuagongshe Chemistry Print Report · For research reference only
{[(6-Benzenesulfonyl-naphthalen-1-ylmethyl)-carbamoyl]-methyl}-methyl-carbamic acid benzyl ester → N-(6-benzenesulfonyl-naphthalen-1-ylmethyl)-2-methylamino-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | {[(6-Benzenesulfonyl-naphthalen-1-ylmethyl)-carbamoyl]-methyl}-methyl-carbamic acid benzyl ester | HCID 59028785 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N-(6-benzenesulfonyl-naphthalen-1-ylmethyl)-2-methylamino-acetamide | HCID 59028776 | — |
Reaction Steps
To a stirring solution of {[(6-Benzenesulfonyl-naphthalen-1-ylmethyl)-carbamoyl]-methyl}-methyl-carbamic acid benzyl ester in methanol and formic acid at room temperature is added palladium on carbon. The mixture is stirred at room temperature, filtered thru Celite, and the filtrate is concentrated to give N-(6-benzenesulfonyl-naphthalen-1-ylmethyl)-2-methylamino-acetamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07799797B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-d6335fbcc22a42f3b08184c090cd2045 |
| Source note | uspto-grants-2010_09 |