HuagongsheHuagongshe Chemistry Print Report · For research reference only
Allyl bromide → 3-Allyloxy-4-methoxybenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Allyl bromide | HCID 7841 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Isovanillin | HCID 12127 | — |
| Reactant | 3-Ethoxy-4-methylbenzaldehyde | HCID 25242058 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3-Allyloxy-4-methoxybenzaldehyde | HCID 534148 | — |
Reaction Steps
The title compound was prepared analogously to 3-ethoxy-4-methyl-benzaldehyde (intermediate B19, vide infra) by reaction of 3-hydroxy-4-methoxy-benzaldehyde with allylbromide in DMF using K2CO3 as base (see also A. W. White, R. Almassy, A. H. Calvert, N. J. Curtin, R. J. Griffin, Z. Hostomsky, K. Maegley, D. R. Newell, S. Srinivasan and B. T. Golding J. Med. Chem. 2000, 43, 4084-4097).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07799806B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-83607a0a8f6e4812b88e46c09a3115c3 |
| Source note | uspto-grants-2010_09 |