HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodoethane → 3-Ethoxy-4-methylbenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodoethane | HCID 6340 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Hydroxy-4-methylbenzaldehyde | HCID 585182 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3-Ethoxy-4-methylbenzaldehyde | HCID 25242058 | — |
Reaction Steps
The title compound was prepared by reaction of commercially available 3-hydroxy-4-methyl-benzaldehyde with ethyl iodide in DMF using K2CO3 as base in analogy to the procedure described in M. J. Ashton, D. C. Cook, G. Fenton, J.-A. Karlsson, M. N. Palfreyman, D. Raeburn, A. J. Ratcliffe, J. E. Souness, S. Thurairatnam and N. Vicker J. Med. Chem. 1994, 37, 1696-1703.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07799806B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-c85d7a67e24948c4a81d68c013fc906b |
| Source note | uspto-grants-2010_09 |