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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1715185Generated: November 2, 2026

1,1'-Carbonyldiimidazole → HCID 59323901, compound

https://huagongshe.com/reaction/1715185

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
ReactantHCID 59323907HCID 59323907—
SolventDichloromethaneHCID 6344—
ProductHCID 59323901HCID 59323901—

Reaction Steps

Dry DCM (10 ml) is added to 1-[4-(2-amino-4-methyl-thiazol-5-yl)-2-fluoro-phenyl]-ethanone (0.25 g, 1.0 mmol) and CDI (0.259 g, 1.6 mmol) and the mixture is heated at reflux for 4 hours. The resulting suspension is filtered and dried under vacuum to afford the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07799810B2
Source datasetuspto-grants-2010_09
ORD IDord-a94a4c45cdae427f930bcdf23140a05e
Source noteuspto-grants-2010_09