Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → Methyl 4-nitrobenzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | 4-Nitrobenzoic Acid | HCID 6108 | — |
| 반응물 | Diazomethane | HCID 9550 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | Methyl 4-nitrobenzoate | HCID 12083 | — |
반응 단계
4-Nitrobenzoic acid (5 g; 29.92 mmol; 1 eq.) is dissolved in toluene (37.5 ml). Timethylsilyl diazomethane in toluene and MeOH (1/1)(45 ml; 2 M; 89.76 mmol; 3 eq.) is added dropwise. The solution is stirred at rt for 2 h. Solvents are removed affording methyl 4-nitrobenzoate as a yellow powder (5.42 g; 100%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07799814B2 |
| 출처 데이터셋 | uspto-grants-2010_09 |
| ORD ID | ord-6600c12735224b1bbc62555e5a9a6cb7 |
| 출처 메모 | uspto-grants-2010_09 |