참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ethylene carbonate | HCID 7303 | — |
| 반응물 | 2,6-Dichloro-4-methylphenol | HCID 17077 | — |
| 촉매 | Imidazole | HCID 795 | — |
| 생성물 | 2-(2,6-Dichloro-4-methylphenoxy)ethan-1-ol | HCID 21396902 | 75% |
반응 단계
In a three-necked flask equipped with a gas droplet counter and an efficient cooling system, a mixture of 2,6-dichloro-p-cresol (20.0 g, 113 mmol), [1,3]dioxolan-2-one (9.95 g, 113 mmol) and imidazole (115 mg, 1.70 mmol) was heated to 160° C. for 25 h. The mixture was allowed to cool to rt. Purification by FC (Et2O/heptane 1.1) yielded the title compound (18.7 g, 75%). LC-MS: tR=0.88 min.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07799805B2 |
|---|
| 출처 데이터셋 | uspto-grants-2010_09 |
|---|
| ORD ID | ord-4dc2c97d68f44f4081e8721cddef7203 |
|---|
| 출처 메모 | uspto-grants-2010_09 |
|---|
