HCID 67148487, compound → HCID 86622971, compound

Participants

Reaction Steps

MnO2 (1.97 g, 20.4 mmol) was added to a sol. of [2-(4-chloro-3-hydroxymethyl-phenyl)-ethyl]-cyclopropyl-carbamic acid tert-butyl ester (1.33 g, 4.08 mmol) in CH3CN (41 mL). The mixture was stirred overnight at rt. The mixture was filtered over Celite, and was washed with CH3CN and CH2Cl2. Evaporation of the filtrate under reduced pressure yielded the crude title compound (1.32 g, quantitative yield) that was used further without purification. LC-MS: tR=1.05 min.

Provenance & Evidence