4-(Trifluoromethyl)benzoyl chloride → HCID 68804501, compound

HRID 1715746Notes

Reaction equation

HRID 1715746 reaction equation
[CH2:1]([CH:3]([N:6]1[CH2:11][CH2:10][CH:9]([CH2:12][CH2:13][CH2:14][C:15]([NH:17][OH:18])=[NH:16])[CH2:8][CH2:7]1)[CH2:4][CH3:5])[CH3:2].[F:19][C:20]([F:31])([F:30])[C:21]1[CH:29]=[CH:28][C:24]([C:25]([Cl:27])=O)=[CH:23][CH:22]=1>>[ClH:27].[CH2:1]([CH:3]([N:6]1[CH2:11][CH2:10][CH:9]([CH2:12][CH2:13][CH2:14][C:15]2[N:16]=[C:25]([C:24]3[CH:23]=[CH:22][C:21]([C:20]([F:19])([F:30])[F:31])=[CH:29][CH:28]=3)[O:18][N:17]=2)[CH2:8][CH2:7]1)[CH2:4][CH3:5])[CH3:2]

Participants

3

Reactant 2

HCID 676074-(Trifluoromethyl)benzoyl chlorideHCID 178446094HCID 178446094, compound

Product 1

HCID 68804501HCID 68804501, compound

Procedure

The title compound was prepared by a similar procedure to that described in Example 3, starting from 4-(1-(1-ethyl-propyl)piperidin-4-yl)-N-hydroxybutyramidine and 4-trifluoromethylbenzoyl chloride.

Sources & evidence

ORD record
ord-df956b9d368e4a3c8835ffedce0f6434
Source dataset
uspto-grants-2010_09
Patent number
US07799924B2

Reaction notes

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