1,2,3,6-Tetrahydro-4-phenylpyridine → HCID 68805844, compound

HRID 1715758Notes

Reaction equation

HRID 1715758 reaction equation
[Cl:1][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[O:13][N:12]=[C:11]([CH2:14][CH:15]3[CH2:20][CH2:19][N:18]([CH:21]([CH2:24][CH3:25])[CH2:22][CH3:23])[CH2:17][CH2:16]3)[N:10]=2)=[CH:5][CH:4]=1.[C:26]1([C:32]2[CH2:33][CH2:34][NH:35][CH2:36][CH:37]=2)[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1>>[ClH:1].[ClH:1].[CH2:22]([CH:21]([N:18]1[CH2:19][CH2:20][CH:15]([CH2:14][C:11]2[N:10]=[C:9]([C:6]3[CH:7]=[CH:8][C:3]([CH2:2][N:35]4[CH2:34][CH:33]=[C:32]([C:26]5[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=5)[CH2:37][CH2:36]4)=[CH:4][CH:5]=3)[O:13][N:12]=2)[CH2:16][CH2:17]1)[CH2:24][CH3:25])[CH3:23]

Participants

3

Reactant 2

HCID 825531,2,3,6-Tetrahydro-4-phenylpyridineHCID 59657777HCID 59657777, compound

Product 1

HCID 68805844HCID 68805844, compound

Procedure

The title compound was prepared by a similar procedure to that described in Example 23, starting from 4-[5-(4-(chloromethyl)phenyl)[1,2,4]oxadiazol-3-ylmethyl]-1-(1-ethylpropyl)piperidine and 4-phenyl-1,2,3,6-tetrahydropyridine. HPLC: Rt=10.24 min.

Sources & evidence

ORD record
ord-be9a89afcf0e4cb9936cdbd35dbfe4c9
Source dataset
uspto-grants-2010_09
Patent number
US07799924B2

Reaction notes

Loading…