4-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridine → HCID 68804480, compound

HRID 1715761Notes

Reaction equation

HRID 1715761 reaction equation
[Cl:1][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[O:13][N:12]=[C:11]([CH2:14][CH:15]3[CH2:20][CH2:19][N:18]([CH:21]4[CH2:25][CH2:24][CH2:23][CH2:22]4)[CH2:17][CH2:16]3)[N:10]=2)=[CH:5][CH:4]=1.[F:26][C:27]1[CH:32]=[CH:31][C:30]([C:33]2[CH2:34][CH2:35][NH:36][CH2:37][CH:38]=2)=[CH:29][CH:28]=1>>[ClH:1].[ClH:1].[CH:21]1([N:18]2[CH2:17][CH2:16][CH:15]([CH2:14][C:11]3[N:10]=[C:9]([C:6]4[CH:7]=[CH:8][C:3]([CH2:2][N:36]5[CH2:35][CH:34]=[C:33]([C:30]6[CH:31]=[CH:32][C:27]([F:26])=[CH:28][CH:29]=6)[CH2:38][CH2:37]5)=[CH:4][CH:5]=4)[O:13][N:12]=3)[CH2:20][CH2:19]2)[CH2:22][CH2:23][CH2:24][CH2:25]1

Participants

3

Reactant 2

HCID 1977484-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridineHCID 68432098HCID 68432098, compound

Product 1

HCID 68804480HCID 68804480, compound

Procedure

The title compound was prepared by a similar procedure to that described in Example 23, starting from 4-[5-(4-chloromethylphenyl)[1,2,4]oxadiazol-3-ylmethyl]-1-cyclopentylpiperidine and 4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridine. HPLC: Rt=11.63 min.

Sources & evidence

ORD record
ord-9fa4659182ce428f893621c1bb99560e
Source dataset
uspto-grants-2010_09
Patent number
US07799924B2

Reaction notes

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