4-Cyclohexylbenzoyl chloride → HCID 59657763, compound
Reaction equation
[CH:1]([N:4]1[CH2:9][CH2:8][CH:7]([C:10]([NH:12][OH:13])=[NH:11])[CH2:6][CH2:5]1)([CH3:3])[CH3:2].[CH:14]1([C:20]2[CH:28]=[CH:27][C:23]([C:24](Cl)=O)=[CH:22][CH:21]=2)[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1>>[CH:1]([N:4]1[CH2:9][CH2:8][CH:7]([C:10]2[N:11]=[C:24]([C:23]3[CH:27]=[CH:28][C:20]([CH:14]4[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]4)=[CH:21][CH:22]=3)[O:13][N:12]=2)[CH2:6][CH2:5]1)([CH3:3])[CH3:2]Participants
3
Procedure
The title compound was prepared by a similar procedure to that described in Example 56, starting from 1-isopropyl-N-hydroxypiperidine-4-carboxamidine and 4-cyclohexylbenzoyl chloride.
Sources & evidence
- ORD record
- ord-817c17fe47d04131a55d88ea8e1f9f78
- Source dataset
- uspto-grants-2010_09
- Patent number
- US07799924B2
Reaction notes
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