Diethyl Ether → HCID 68510931, compound

Participants

Reaction Steps

To 2-methoxybenzylamine (30 mmol, 4.12 g) was added ether (6 ml) and acetic acid (glacial, 10 ml). The resulting solution was cooled on an ice-batch and Br2 (30 mmol, 4.79 g, 1.54 ml) was added dropwise. After 1 h the ice-bath was removed and the mixture was stirred for another 1 h before addition of ether (20 ml). The resulting mixture was left in the cold for 0.5 h, the solids were filtered off and washed with ether (20 ml) to give a cream colored solid (6.29 g). The crude product was crystallized in ethanol/ether to give the title compound (4.62 g, 52%) as white crystalline material. 1H NMR (DMSO, 500 MHz) δ 3.84 (s, 3H), 3.98 (s, 2H), 7.05 (s, 1H), 7.58 (m, 2H) and 8.16. (br, 3H).

Provenance & Evidence