HCID 22065264, compound → HCID 22065266, compound

HRID 1715871Notes

Reaction equation

HRID 1715871 reaction equation
[OH:1][C:2]1[CH:7]=[C:6]([OH:8])[CH:5]=[CH:4][C:3]=1[C:9](=[O:20])[C:10]([C:12]1[CH:17]=[CH:16][C:15]([OH:18])=[C:14]([OH:19])[CH:13]=1)=[CH2:11].[H][H]>CO.[Pd]>[OH:1][C:2]1[CH:7]=[C:6]([OH:8])[CH:5]=[CH:4][C:3]=1[C:9](=[O:20])[CH:10]([C:12]1[CH:17]=[CH:16][C:15]([OH:18])=[C:14]([OH:19])[CH:13]=1)[CH3:11]

Participants

5

Reactant 2

HCID 22065264HCID 22065264, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 22065266HCID 22065266, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

The title compound was obtained by catalytic hydrogenation of 1-(2,4-dihydroxyphenyl)-2-(3′,4′-dihydroxyphenyl)-1-oxo-2-propene obtained as in Example 3 or Example 4. To a solution of 1-(2,4-dihydroxyphenyl)-2-(3′,4′-dihydroxyphenyl)-1-oxo-2-propene in methanol was added palladium on carbon, and hydrogen gas was bubbled vigorously through the solution for ten minutes. Removal of the catalyst and evaporation of the solvent afforded the title compound.

Workup

  1. customobtained as in Example 3 or Example 4
  2. customwas bubbled vigorously through the solution for ten minutes
  3. customRemoval of the catalyst and evaporation of the solvent

Sources & evidence

ORD record
ord-c901c217233c4b91bee5a5adce91292d
Source dataset
uspto-grants-2010_09
Patent number
US07799955B2

Reaction notes

Loading…