Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | Benzenamine, 4-(triphenylmethyl)- | HCID 89914 | — |
| Reactant | Sodium Nitrite | HCID 23668193 | — |
| Catalyst | copper(I) bromide | HCID 24593 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 59133385 | HCID 59133385 | 86% |
Reaction Steps
25 parts by weight of 4-tritylaniline, 400 parts by weight of acetone, and 162 parts by weight of hydrobromic acid were put into a reaction vessel and stirred. While cooling the vessel in an ice bath, a solution of 7 parts by weight of sodium nitrite dissolved in 100 parts by weight of water was slowly added dropwise thereto. After the dropwise addition was complete, stirring was carried out for 30 minutes in an ice bath. Slowly added dropwise to this solution in an ice bath was a solution of 17.4 parts by weight of copper (I) bromide that had been dissolved in 31.5 parts by weight of hydrobromic acid. After the dropwise addition was complete, stirring was carried out at room temperature for 2 hours. After the reaction, a precipitate deposited in the reaction solution was collected by filtration, thus giving 25.8 parts by weight of 4-tritylbromobenzene (yield: 86%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07799949B2 |
|---|
| Source dataset | uspto-grants-2010_09 |
|---|
| ORD ID | ord-0eb6b09969544f54a5d8b3fc683348d1 |
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| Source note | uspto-grants-2010_09 |
|---|
