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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1716237Generated: October 31, 2026

2-Chloro-1-(1,2,3,4-tetrahydroquinolin-1-yl)ethan-1-one → HCID 1169875, compound

https://huagongshe.com/reaction/1716237

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-1-(1,2,3,4-tetrahydroquinolin-1-yl)ethan-1-oneHCID 240137—
ReactantHCID 178479924HCID 178479924—
ProductHCID 1169875HCID 116987542%

Reaction Steps

The title compound was synthesized according to General Procedure A using compound 4 as the electrophile and 1-methyl-5-phenyl-1H-imidazole-2-thiol as the nucleophile to yield 28 as an off-white solid (42%): MS m/z: 364 (M+H)+. Anal. Calcd. For, C21H21N3OS: C, 69.39; H, 5.82; N, 11.56; S, 8.82. Found: C, 69.29; H, 5.83; N, 11.40; S, 8.83.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07803790B2
Source datasetuspto-grants-2010_09
ORD IDord-6f3b7d2f71f145819458c771f9e75caa
Source noteuspto-grants-2010_09