2-Chloro-1-(1,2,3,4-tetrahydroquinolin-1-yl)ethan-1-one → 2-(4-tert-butylthiazol-2-ylthio)-1-(3,4-dihydroquinolin-1(2H)-yl)ethanone

Participants

Reaction Steps

The title compound was synthesized according to General Procedure A using compound 4 as the electrophile and 4-tert-butylthiazole-2-thiol as the nucleophile to yield 34 (37%): MS: m/z+347.2 [M+H]+. Anal. Calcd (found) for C18H22N2OS2: C, 62.39; (62.60), H, 6.40; (6.43), N, 8.08; (8.06), S, 18.50; (18.39).

Provenance & Evidence