2-(2-Benzothiazolylthio)acetic acid → HCID 59467902, compound

HRID 1716246Notes

Reaction equation

HRID 1716246 reaction equation
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[S:10][CH2:11][C:12]([OH:14])=O.[F:15][C:16]1[CH:24]=[C:23]2[C:19]([CH2:20][CH2:21][NH:22]2)=[CH:18][CH:17]=1>>[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[S:10][CH2:11][C:12]([N:22]1[C:23]2[C:19](=[CH:18][CH:17]=[C:16]([F:15])[CH:24]=2)[CH2:20][CH2:21]1)=[O:14]

Participants

3

Reactant 2

HCID 805252-(2-Benzothiazolylthio)acetic acidHCID 2604006-fluoro-2,3-dihydro-1H-indole

Product 1

HCID 59467902HCID 59467902, compoundYield 70%

Procedure

The title compound was synthesized according to General Procedure B using 2-(benzo[d]thiazol-2-ylthio)acetic acid and 6-fluoroindoline to yield 43 as a white solid (70%): MS m/z: 345 (M+H)+. Anal. Calcd. For, C17H13N2FOS2: C, 59.28; H, 3.80; N, 8.13; S, 18.62; F, 5.52. Found: C, 59.51; H, 3.85; N, 8.13; S, 18.73; F, 5.37.

Workup

  1. customThe title compound was synthesized

Sources & evidence

ORD record
ord-cb53add2a8e34202a17e9df12cce7574
Source dataset
uspto-grants-2010_09
Patent number
US07803790B2

Reaction notes

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