Pyridine → HCID 59468456, compound

Participants

Reaction Steps

[5-(2-Chloro-pyrimidin-4-yl)-thiophen-2-ylmethyl]-(4-methoxybenzyl)-amine (22 mg, 0.063 mmol) was dissolved in CH2Cl2 (1 mL) and treated with pyridine (4.3 uL, 0.076 mmol) and Et3N (17.8 uL, 0.127 mmol), followed by benzoyl chloride (8.9 uL, 0.765 mmol). The mixture was allowed to stir for 18 h and was then washed with 1 N HCl, dried over Na2SO4 and concentrated. The material was used crude in the next step.

Provenance & Evidence