[3-(1H-Indol-7-yl)-3-phenyl-propyl]-methyl-amine → HCID 59831633, compound

HRID 1716643Notes

Reaction equation

HRID 1716643 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([CH:10]([C:16]3[CH:21]=[CH:20][CH:19]=[C:18]([O:22][CH3:23])[CH:17]=3)[CH2:11][C:12]([NH:14][CH3:15])=O)[CH:8]=2)[CH:3]=[CH:2]1.N1C2C(=CC=CC=2C(C2C=CC=CC=2)CCNC)C=C1>>[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([CH:10]([C:16]3[CH:21]=[CH:20][CH:19]=[C:18]([O:22][CH3:23])[CH:17]=3)[CH2:11][CH2:12][NH:14][CH3:15])[CH:8]=2)[CH:3]=[CH:2]1

Participants

3

Reactant 2

HCID 17747555[3-(1H-Indol-7-yl)-3-phenyl-propyl]-methyl-amineHCID 59831810HCID 59831810, compound

Product 1

HCID 59831633HCID 59831633, compoundYield 94%

Procedure

[3-(1H-Indol-6-yl)-3-(3-methoxy-phenyl)-propyl]-methyl-amine XXXIII (100 mg, 94% yield) was prepared as a hydrochloride salt from 3-(1H-indol-6-yl)-3-(3-methoxy-phenyl)-N-methyl-propionamide using the procedure described for [3-(1H-Indol-7-yl)-3-phenyl-propyl]-methyl-amine XX (see Example 4). MS (M+H)=295.

Sources & evidence

ORD record
ord-a01b99bb05b04786a2638187d6c8fee2
Source dataset
uspto-grants-2010_09
Patent number
US07803830B2

Reaction notes

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