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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1716668Generated: October 31, 2026

5-Bromoindole → 5-Bromo-3-cyanoindole

https://huagongshe.com/reaction/1716668

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-BromoindoleHCID 24905—
Reactant4-Bromo-1H-indole-3-carbonitrileHCID 2763232—
Product5-Bromo-3-cyanoindoleHCID 362335466%

Reaction Steps

5-Bromo-1H-indole-3-carbonitrile LXII (3.72 g, 66% yield) was prepared from 5-bromo-indole using the procedure described for 4-bromo-1H-indole-3-carbonitrile LVII (see Example 14).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07803830B2
Source datasetuspto-grants-2010_09
ORD IDord-3eba352ba3174983b11bdb3a1cf2b072
Source noteuspto-grants-2010_09