HCID 59831784, compound → HCID 25261575, compound

HRID 1716687Notes

Reaction equation

HRID 1716687 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:13]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH2:14][CH2:15]O)[CH:5]=[C:6]2[C:10]=1[NH:9][CH:8]=[C:7]2[C:11]#[N:12].[CH3:23][NH:24]CCC(C1C=C2C(=CC=1)NC=C2C#N)C1C=CC=CC=1>>[F:1][C:2]1[CH:3]=[C:4]([CH:13]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH2:14][CH2:15][NH:24][CH3:23])[CH:5]=[C:6]2[C:10]=1[NH:9][CH:8]=[C:7]2[C:11]#[N:12]

Participants

3

Reactant 2

HCID 59831784HCID 59831784, compoundHCID 67356444HCID 67356444, compound

Product 1

HCID 25261575HCID 25261575, compound

Procedure

7-Fluoro-5-(3-Methylamino-1-phenyl-propyl)-1H-indole-3-carbonitrile LXXXIX (197 mg) was prepared from 7-fluoro-5-(3-hydroxy-1-phenyl-propyl)-1H-indole-3-carbonitrile using the procedure described above for preparation of 5-(3-Methylamino-1-phenyl-propyl)-1H-indole-3-carbonitrile LXVI (Example 16). MS (M+H)=308.

Sources & evidence

ORD record
ord-b7cdf48e163b4a60bf73ee02ca112404
Source dataset
uspto-grants-2010_09
Patent number
US07803830B2

Reaction notes

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