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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1716691Generated: October 27, 2026

5-bromo-7-methoxy-1H-indole → 3-(7-Methoxy-1H-indol-5-yl)-3-phenyl-acrylic acid ethyl ester

https://huagongshe.com/reaction/1716691

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-bromo-7-methoxy-1H-indoleHCID 19804063—
Reactant3-(7-Methoxy-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl esterHCID 67356083—
Product3-(7-Methoxy-1H-indol-5-yl)-3-phenyl-acrylic acid ethyl esterHCID 6735573350%

Reaction Steps

3-(7-Methoxy-1H-indol-5-yl)-3-phenyl-acrylic acid ethyl ester CVI (120 mg, 50% yield) was prepared from 5-bromo-7-methoxyindole using the procedure described above for preparation of 3-(7-Methoxy-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl ester LIII (Example 13).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07803830B2
Source datasetuspto-grants-2010_09
ORD IDord-1712a81de952435092df48fc2525d16a
Source noteuspto-grants-2010_09