HCID 59831784, compound → HCID 59831658, compound

HRID 1716697Notes

Reaction equation

HRID 1716697 reaction equation
O[CH2:2][CH2:3][CH:4]([C:11]1[CH:19]=[C:18]([O:20][CH3:21])[CH:17]=[C:16]2[C:12]=1[C:13]([C:22]#[N:23])=[CH:14][NH:15]2)[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1.[CH3:24][NH:25]CCC(C1C=C2C(=CC=1)NC=C2C#N)C1C=CC=CC=1>>[CH3:21][O:20][C:18]1[CH:17]=[C:16]2[C:12]([C:13]([C:22]#[N:23])=[CH:14][NH:15]2)=[C:11]([CH:4]([C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH2:3][CH2:2][NH:25][CH3:24])[CH:19]=1

Participants

3

Reactant 2

HCID 59831784HCID 59831784, compoundHCID 67355324HCID 67355324, compound

Product 1

HCID 59831658HCID 59831658, compound

Procedure

6-Methoxy-4-(3-methylamino-1-phenyl-propyl)-1H-indole-3-carbonitrile CXXXII (90 mg) was prepared from 4-(3-hydroxy-1-phenyl-propyl)-6-methoxy-1H-indole-3-carbonitrile using the procedure described above for preparation of 5-(3-Methylamino-1-phenyl-propyl)-1H-indole-3-carbonitrile LXVI. MS (M+H)=320.

Sources & evidence

ORD record
ord-306a8f2df0df458294bc131a0c2663de
Source dataset
uspto-grants-2010_09
Patent number
US07803830B2

Reaction notes

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