3-(1H-Indol-7-yl)-N-methyl-3-phenyl-propionamide → N-Methyl-3-(1-methyl-1H-indol-6-yl)-3-phenyl-propionamide

HRID 1716707Notes

Reaction equation

HRID 1716707 reaction equation
[CH3:1][NH:2][C:3](=[O:22])[CH:4]=[C:5]([C:12]1[CH:20]=[C:19]2[C:15]([CH:16]=[CH:17][N:18]2[CH3:21])=[CH:14][CH:13]=1)[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.N1C2C(=CC=CC=2C(C2C=CC=CC=2)CC(NC)=O)C=C1>>[CH3:1][NH:2][C:3](=[O:22])[CH2:4][CH:5]([C:12]1[CH:20]=[C:19]2[C:15]([CH:16]=[CH:17][N:18]2[CH3:21])=[CH:14][CH:13]=1)[C:6]1[CH:7]=[CH:8][CH:9]=[CH:10][CH:11]=1

Participants

3

Reactant 2

HCID 598317453-(1H-Indol-7-yl)-N-methyl-3-phenyl-propionamideHCID 67355247N-Methyl-3-(1-methyl-1H-indol-6-yl)-3-phenyl-acrylamide

Product 1

HCID 59831892N-Methyl-3-(1-methyl-1H-indol-6-yl)-3-phenyl-propionamide

Procedure

N-Methyl-3-(1-methyl-1H-indol-6-yl)-3-phenyl-propionamide CXLV was prepared from N-Methyl-3-(1-methyl-1H-indol-6-yl)-3-phenyl-acrylamide using the procedure described above for preparation of 3-(1H-Indol-7-yl)-N-methyl-3-phenyl-propionamide XIX (Example 4).

Sources & evidence

ORD record
ord-db310caeea114c3eb38c24e51f59a07b
Source dataset
uspto-grants-2010_09
Patent number
US07803830B2

Reaction notes

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