5-bromo-3-methoxy-1H-indazole → 3-(3-methoxy-1H-indazol-5-yl)-3-phenyl-acrylic acid ethyl ester

HRID 1716746Notes

Reaction equation

HRID 1716746 reaction equation
Br[C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][N:6]=[C:5]2[O:11][CH3:12].[CH2:13]([O:15][C:16](=[O:36])[CH:17]=[C:18](C1C=CC(OC)=C2C=1C=CN2)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[CH3:14]>>[CH2:13]([O:15][C:16](=[O:36])[CH:17]=[C:18]([C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][N:6]=[C:5]2[O:11][CH3:12])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[CH3:14]

Participants

3

Reactant 2

HCID 598317605-bromo-3-methoxy-1H-indazoleHCID 673560833-(7-Methoxy-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl ester

Product 1

HCID 673551473-(3-methoxy-1H-indazol-5-yl)-3-phenyl-acrylic acid ethyl ester

Procedure

3-(3-Methoxy-1H-indazol-5-yl)-3-phenyl-acrylic acid ethyl ester CCXI was prepared from 5-bromo-3-methoxy-1H-indazole, using the procedure described for preparation of 3-(7-Methoxy-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl ester LIII (Example 13).

Sources & evidence

ORD record
ord-59c40e21ad8f401aa9bc6d5273acbe4d
Source dataset
uspto-grants-2010_09
Patent number
US07803830B2

Reaction notes

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