Cyclobutanecarbonyl chloride → HCID 66938901, compound

Participants

Reaction Steps

Prepare according to procedure in Example 69 starting with N-Methyl-N-(1-methyl-piperidin-4-yl)-pyridine-2,6-diamine (Preparation 34) (175 mg, 0.794 mmol), cyclobutanecarbonyl chloride (136 μL, 1.19 mmol), and pyridine (15 mL) to yield 237 mg (88%) of the title compound: mass spectrum (ion spray): m/z=303.1 (M+1); Analysis Calcd for C17H27N4OCl.0.1H2O: C, 59.93; H, 8.05; N, 16.45. Found: C, 59.81; H, 7.93; N, 16.45. mp 258-60° C.

Provenance & Evidence