Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1717021생성일: 2026년 10월 25일
Phenylboronic Acid → (3-[(4-Chloro-biphenyl-3-carbonyl)-amino]-phenyl)-acetic acid ethyl ester
https://huagongshe.com/reaction/1717021
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Phenylboronic Acid | HCID 66827 | — |
| 반응물 | [3-(5-Bromo-2-chlorobenzoylamino)phenyl]acetic acid ethyl ester | HCID 59654675 | — |
| 생성물 | (3-[(4-Chloro-biphenyl-3-carbonyl)-amino]-phenyl)-acetic acid ethyl ester | HCID 59654748 | — |
반응 단계
[3-(5-Bromo-2-chloro-benzoylamino)-phenyl]-acetic acid ethyl ester (198 mg, 0.50 mmol) was coupled to phenylboronic acid using Method E, except that the reaction mixture was heated at 80° C. for 25 min. The crude product was purified by column chromatography using 20% EtOAc in heptane to give the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US07803841B2 |
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| 출처 데이터셋 | uspto-grants-2010_09 |
|---|
| ORD ID | ord-197df6e5b5eb4bd48e6c8706a47456ee |
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| 출처 메모 | uspto-grants-2010_09 |
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