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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1717036Generated: November 1, 2026

2-phenyl-1H-imidazole-4-carboxylic acid → {3-[(2-phenyl-1H-imidazole-5-carbonyl)-amino]-phenyl}acetic acid ethyl ester

https://huagongshe.com/reaction/1717036

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-phenyl-1H-imidazole-4-carboxylic acidHCID 2738139—
ReactantEthyl 2-(3-aminophenyl)acetateHCID 13042040—
Product{3-[(2-phenyl-1H-imidazole-5-carbonyl)-amino]-phenyl}acetic acid ethyl esterHCID 59654856—

Reaction Steps

2-Phenyl-1H-imidazole-5-carboxylic acid (105 mg, 0.56 mmol) was coupled with ethyl ester (6) (100 mg, 0.56 mmol) following Method C to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07803841B2
Source datasetuspto-grants-2010_09
ORD IDord-43a70a5315b6415892c7f6389a881e9f
Source noteuspto-grants-2010_09