5-Phenylfuran-2-carboxylic acid → HCID 59654865, compound

HRID 1717049Notes

Reaction equation

HRID 1717049 reaction equation
[C:1]1([C:7]2[O:11][C:10]([C:12]([OH:14])=O)=[CH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:15][O:16][C:17](=[O:27])[CH2:18][CH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[C:22]([NH2:26])[CH:21]=1>>[CH3:15][O:16][C:17](=[O:27])[CH2:18][CH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[C:22]([NH:26][C:12]([C:10]2[O:11][C:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)=[CH:8][CH:9]=2)=[O:14])[CH:21]=1

Participants

3

Reactant 2

HCID 7362555-Phenylfuran-2-carboxylic acidHCID 10442275Methyl 3-(3-aminophenyl)propanoate

Product 1

HCID 59654865HCID 59654865, compound

Procedure

5-Phenyl-furan-2-carboxylic acid (56) (40 mg, 0.21 mmol) was coupled to 3-(3-amino-phenyl)-propionic acid methyl ester (41 mg, 0.23 mmol) using Method D to give the title compound.

Sources & evidence

ORD record
ord-a37254e21cfd4e90ac07edd4ccb8ba25
Source dataset
uspto-grants-2010_09
Patent number
US07803841B2

Reaction notes

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