HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminocinnamic acid ethyl ester → 3-(3-[(4,4'-Difluoro-biphenyl-3-carbonyl)-amino]-phenyl)-acrylic Acid Ethyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminocinnamic acid ethyl ester | HCID 97825 | — |
| Reactant | 4,4'-Difluoro-[1,1'-biphenyl]-3-carboxylic acid | HCID 46312333 | — |
| Product | 3-(3-[(4,4'-Difluoro-biphenyl-3-carbonyl)-amino]-phenyl)-acrylic Acid Ethyl Ester | HCID 68497396 | — |
Reaction Steps
4,4′-Difluoro-biphenyl-3-carboxylic acid (100 mg, 0.43 mmol) was coupled to aniline (60) (82 mg, 0.43 mmol) using Method C to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07803841B2 |
| Source dataset | uspto-grants-2010_09 |
| ORD ID | ord-efbdb21851da4d31a718360fae887693 |
| Source note | uspto-grants-2010_09 |