5-Bromo-2-furanecarboxylic acid → HCID 59654699, compound

HRID 1717154Notes

Reaction equation

HRID 1717154 reaction equation
[Br:1][C:2]1[O:6][C:5]([C:7]([OH:9])=O)=[CH:4][CH:3]=1.[CH2:10]([O:12][C:13](=[O:23])[CH2:14][CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[C:18]([NH2:22])[CH:17]=1)[CH3:11]>>[CH2:10]([O:12][C:13](=[O:23])[CH2:14][CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[C:18]([NH:22][C:7]([C:5]2[O:6][C:2]([Br:1])=[CH:3][CH:4]=2)=[O:9])[CH:17]=1)[CH3:11]

Participants

3

Reactant 2

HCID 685115-Bromo-2-furanecarboxylic acidHCID 82314Ethyl 3-(3-Aminophenyl)propionate

Product 1

HCID 59654699HCID 59654699, compound

Procedure

5-Bromo-2-furoic acid (247 mg, 1.29 mmol) was coupled to aniline (124) (250 mg, 1.29 mmol) using Method C to give the title compound.

Sources & evidence

ORD record
ord-2cfb9789991047c39eb9f4be5a7f0e78
Source dataset
uspto-grants-2010_09
Patent number
US07803841B2

Reaction notes

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