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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1717744Generated: October 26, 2026

HCID 57884497, compound → 3-[4-(4-Acetyl-3-hydroxy-2-propyl-phenoxymethyl)-benzoyl]-benzoic acid

https://huagongshe.com/reaction/1717744

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 57884497HCID 57884497—
Reactant3-[4-(4-Acetyl-3-hydroxy-2-propyl-phenoxymethyl)-benzoyl]-benzonitrileHCID 66699556—
Product3-[4-(4-Acetyl-3-hydroxy-2-propyl-phenoxymethyl)-benzoyl]-benzoic acidHCID 57884479100%

Reaction Steps

The title compound is prepared essentially as described for 3-{[4-(4-acetyl-3-hydroxy-2-propyl-phenoxymethyl)-phenyl]-hydroxy-methyl}-benzoic acid employing 3-[4-(4-acetyl-3-hydroxy-2-propyl-phenoxymethyl)-benzoyl]-benzonitrile, to give the title compound (52 mg, 100%), as a white powder. 1H NMR (DMSO-d6) δ 13.34 (bs, 1H), 12.89 (s, 1H), 8.22-8.26 (m, 2H), 8.01 (d, 1H), 7.82-7.87 (m, 3H), 7.75 (t, 1H), 7.65-7.68 (m, 2H), 6.75 (d, 1H), 5.42 (s, 2H), 2.60-2.68 (m, 5H), 1.50-1.55 (m, 2H), 0.91 (t, 3H). LCMS M−1 431.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07803938B2
Source datasetuspto-grants-2010_09
ORD IDord-b5b348ad0cdf4dcd999caf2004f3265c
Source noteuspto-grants-2010_09